Prof. Machang’u is a microbiologist at the Pest Management Centre, and Department of Veterinary Microbiology and Parasitology, Sokoine University of Agriculture.
He is one of founders of the Pest Management Centre that was formerly known as Rodent Research Project. Prof Machang’u was the first Director of the SUA Pest Management Centre, in the year 2000, and a co-founder of the SUA APOPO Rodent Biosensor Technology research, which is now operational in Tanzania, Mozambique, Angola and Cambodia.
He also coordinated the university wide infrastructural and academic development program (acro. SUA-VLIR), which was a joint venture involving SUA and the Belgian Government.
Prof. Machang’u is an avid advocate against tobacco use, and through his engagement in this field he rose to become the Chairperson of a national NGO, the Tanzania Public Health Association for the period 2004 to 2008).